<dd id="fncnt"><pre id="fncnt"></pre></dd>

  • WNT信號通路DNA甲基化PCR芯片 WNT Signaling Pathway DNA Methylation PCR Array

    科技服務 > 生物芯片實驗服務 > WNT信號通路DNA甲基化PCR芯片 WNT Signaling Pathway DNA Methylation PCR Array

    WNT信號通路DNA甲基化PCR芯片 WNT Signaling Pathway DNA Methylation PCR Array

    Cancer Inflammation & Immunity Crosstalk PCR Array
    運費 ¥0.00
    (庫存 9999 件)
    Human WNT Signaling Pathway DNA Methylation PCR Array, Signature Panel: 
    EAHS-431Z


    The Human WNT Signaling Pathway EpiTect Methyl II Signature PCR Array profiles the promoter methylation status of a panel of 22 promoters of genes involved in WNT signaling during carcinogenesis and cellular differentiation. Hypermethylation of WNT pathway inhibitory proteins (NKD1 and WIF1) causes activation of WNT signaling as well as uncontrolled cell proliferation, a hallmark of cancer. Hypermethylation of WNT ligand genes (such as WNT10B) down-regulates expression during differentiation (e.g., adipogenesis). Profiling cellular or fresh tissue genomic DNA samples with these arrays may help correlate CpG island methylation status with biological phenotypes. The results may also help provide further insights into how WNT signaling contributes to carcinogenesis and cellular differentiation. With a simple restriction enzyme digestion and real-time PCR, research studies can analyze the promoter methylation status of 22 different WNT signaling pathway members with this DNA methylation PCR array.
    Both 96-well and 384-well ( 4 X 96 ) formats are available




    WNT Signaling Pathways:
    Canonical: CTBP1, CXXC4, FZD1, FZD2, FZD4, FZD5, FZD8, FZD9, GSK3A, GSK3B, LEF1, NKD1, SENP2, SFRP4, SOX17, WIF1, WNT1, WNT10A, WNT10B, WNT6.
    Planar Cell Polarity (PCP): NKD1, WNT9A.
    WNT/Ca+2: FZD2, WNT1, WNT10A, WNT10B, WNT5A, WNT6, WNT9A.
    WNT Signaling Negative Regulation: CTBP1, CXXC4, NKD1, SENP2, SFRP4, SOX17, WIF1.
    WNT Signaling Components:
    Ligands & Cofactors: SFRP4, WIF1, WNT1, WNT10A, WNT10B, WNT5A, WNT6, WNT9A.
    Receptors: FZD1, FZD2, FZD4, FZD5, FZD8, FZD9.
    Downstream Signaling: CXXC4, GSK3A, GSK3B, NKD1, SENP2, SOX17.
    Transcription Factors & Cofactors: CTBP1, LEF1.


    姓名
    電話號碼
    電子郵箱
    公司名稱
    地址
    留言*
     
    驗證碼
    提交
    999国产精品永久免费视频,free性朝鲜娇小videos,亚洲高清国产拍精品26u,东北女人毛多水多牲交视频